Dear all, After adjusting F.p.value (method="fdr") from a time course analysis and selecting values < 0.05, I get no significant genes. However, when I look at the F.p.values the are quite small (10^ - 5). Why is it that there are no significant genes after F.p.value adjustment?? Sorry, I am not a statistician. Thanks. Sohail Khan Scientific Programmer COLD SPRING HARBOR LABORATORY Genome Research Center 500 Sunnyside Boulevard Woodbury, NY 11797 (516)422-4076