anybody familiar with method to calculate which residues are involved in a hydrophobic core given a 3D structure profile of a protein? i working on DHFR (PDB 3IA4), and using CIF file to have a 3D xyz map. I want to compare what i think are hydrophobic core just by looking at 3D structure, and what the computer suggest me. can you help me find a code that can do this stuff?