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Hi Sanchita, You can get annotation packages using biocLite(). To get the u133a chip info: source("http://www.bioconductor.org/biocLite.R") biocLite("hgu133aprobe") biocLite("hgu133acdf") should do it Aedin Message: 7 Date: Fri, 25 Aug 2006 16:43:18 -0700 (PDT) From: Sanchita Bhattacharya <sanchita_c@yahoo.com> Subject: [BioC] High Throughput Affy Arrays To: bioconductor at stat.math.ethz.ch Message-ID: <20060825234318.8040.qmail at web56103.mail.re3.yahoo.com> Content-Type: text/plain Hi, I am trying to normalize 64 High Throughput Affy Human arrays in Bioconductor using GCRMA package. One of the hurdles in running justgcrma() is under MetaData section on Bioconductor site I didn't find the HT_Hgu133A cdf and probe files. Does anybody has any clue. I was able to download the HT_Hgu133A cdf file from the Affy Netaffx site but don't know how to make a package out of it that would run on Bioconductor. Any help on this matter will be highly apprecaited. Thanks, Sanchita P.S.I went to the following link to look for cdf packages: http://www.bioconductor.org/packages/1.8/ChipName.html