Rgraphviz has been updated in the release branch of Bioconductor 1.9. The new version 1.12.3 replaces 1.12.1 (1.12.2 was visible 1-2 days in the repository). The update makes it possible to use Rgraphviz with Graphviz version 2.10 and 2.12 (as well as the odd numbered development versions 2.9 and 2.11). There is no added functionality nor bug fixes so current users of Rgraphviz do not need to update their version. Some added comments on (R)Graphviz: * It is known that on certain platforms Graphviz 2.8 (and 2.4, 2.6) has problems laying out a graph containing singleton nodes with the neato algorithm, such as the first graph in the vignette. This problem results in a segmentation fault and subsequent crash of the R session. The easiest fix is to update Graphviz. * When installing Graphviz be aware that I have seen problems on the Mac OS X Power PC platform when Graphviz is compiled with optimization. This problem may or may not persist across platforms. Kasper