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Hi, Mayte, The hgu133a2 you are using is the most updated version in bioconductor, but the source data that we used to build this package was download in Aug, 2006. There will be more updated data packages (source and windows binaries) available before next Thursday (actually maybe this Thursday). I checked the updated "hgu133a" I have here and both "05218" and "04916" are on the pathway list. So, please wait a couple of days. best nianhua