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davidl@unr.nevada.edu
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140
@davidlunrnevadaedu-1371
Last seen 10.2 years ago
Hello all,
I was just wondering if there is an easy way to start with a list
of Gene
Ontology terms and to end with an interpretable map of their
inter-relationships. This would hopefully either connect terms that
are
siblings/parents/children of one another or would spit out an induced
GO graph
with the listed Gene Ontology terms labeled. The reason I was
wondering if
something like this exists is that I obtained a list of 365 over
represented
Gene Ontology terms in a subset of my data using the hyperGTest
function (with
conditional being true) but this list contains a lot of terms which
appear to
be closely related to one another (despite ignoring genes of
significantly over
represented children terms in determining over representation of the
parents).
I would like to be able to see how the terms are related to each
other
visually so that I could more easily pick for verification GO terms
(and genes
belonging to these GO terms) that seem appropriately representative of
the
related groups. I am definately open to any suggestions that would
accomplish
this sort of thing, including the names of package Vignettes which I
have
failed to read completely. Thank you very much in advance,
Dave