Hello- I'm interested in comparing PLIER-summarized Affymetrix GeneChip data to RMA-summarized data. I plan to use v1.4.0 of the plier package, and I'm running it on a SUN box (sparc-sun-solaris2.10). I was searching the Bioconductor mailing list archives, and I came across a message (dated November 22, 2006) that mentioned that different results were obtained when using justPlier (plier package v1.4.0) on a UNIX machine compared to using it on a PC or Linux machine. There was no subsequent response to this message listed in the archives. Has anyone else encountered a similar problem? If so, are there any known solutions (e.g. changing default parameters in justPlier)? I would like to avoid summarizing my data on a PC due to the large number of CEL files that make up this experiment. Thank you very much! Michael Pickard This e-mail, including any attachments, is a confidential business communication, and may contain information that is confidential, proprietary and/or privileged. This e-mail is intended only for the individual(s) to whom it is addressed, and may not be saved, copied, printed, disclosed or used by anyone else. If you are not the(an) intended recipient, please immediately delete this e-mail from your computer system and notify the sender. Thank you.