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Hi Malick, Malick.PAYE at eu.biomerieux.com wrote: > hello, > > I work for an invitro diagnostic company www.biomerieux.com) and we are > interested in microarray data analysis (we are working with affymetrix > chips). > > I would like to know if Mismatch are used in RMA background correction > method for the estimation of some parameters of the underlying model. The quick answer is no. You might want to read some of the papers describing this method which will clarify the background estimation. See here for a selection: http://www.biostat.jhsph.edu/~ririzarr/papers/index.html Best, Jim > > Thanks in advance. > > M.P > > Malick Paye | bioM?rieux | Biomathematician > Phone: (+33)4 78 87 70 97 | Fax: (+33)4 78 87 53 40 > [Centre Cristophe M?rieux, 5 Rue des Berges, 38004 Cedex 01 Grenoble, > France] > > > -------------------------------------------------------------------- --------- > AVIS : Ce courrier et ses pieces jointes sont destines a leur seul destinataire et peuvent contenir des informations confidentielles appartenant a bioMerieux. Si vous n'etes pas destinataire, vous etes informe que toute lecture, divulgation, ou reproduction de ce message et des pieces jointes est strictement interdite. Si vous avez recu ce message par erreur merci d'en prevenir l'expediteur et de le detruire, ainsi que ses pieces jointes. > > NOTICE: This message and attachments are intended only for the use of their addressee and may contain confidential information belonging to bioMerieux. If you are not the intended recipient, you are hereby notified that any reading, dissemination, distribution, or copying of this message, or any attachment, is strictly prohibited. If you have received this message in error, please notify the original sender immediately and delete this message, along with any attachments. > > [[alternative HTML version deleted]] > > > > -------------------------------------------------------------------- ---- > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor ********************************************************** Electronic Mail is not secure, may not be read every day, and should not be used for urgent or sensitive issues.