Exonmap mapping problems
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@tore-eriksson-2346
Last seen 10.2 years ago
Hello everybody! I have encountered some strange behaviour when using the mapping functions in the exonmap package. The results are inconsistent for different length inputs, and for long lists there is no result at all. Some examples and the sessionInfo follows below. Shown are results for probest.to.exon, but probeset.to.gene gives similar results. Any tips are most welcome. Tore > xmapDatabase("Human") Switching to human database... done. > length(sigs) [1] 1865 > probeset.to.exon(sigs, debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece NULL > sigs[1:14] [1] "2315924" "2316106" "2318791" "2319627" "2320571" "2320764" "2321153" [8] "2321396" "2322705" "2323289" "2326877" "2328133" "2330669" "2331628" > probeset.to.exon(sigs[1:9], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" "ENSE00001400447" "ENSE00001422373" "ENSE00001469531" [9] "ENSE00001469483" "ENSE00001424556" "ENSE00001469369" "ENSE00001374956" > probeset.to.exon(sigs[1:10], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece NULL > probeset.to.exon(sigs[2:10], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" "ENSE00001400447" "ENSE00001422373" "ENSE00001469531" [9] "ENSE00001469483" "ENSE00001424556" "ENSE00001469369" "ENSE00001374956" > probeset.to.exon(sigs[2:11], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" > sessionInfo() R version 2.5.0 (2007-04-23) ia64-unknown-linux-gnu locale: LC_CTYPE=ja_JP.UTF-8;LC_NUMERIC=C;LC_TIME=C;LC_COLLATE=C;LC_MONETARY=C ;LC_MESSAGES=C;LC_PAPER=C;LC_NAME=C;LC_ADD RESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=C;LC_IDENTIFICATION=C attached base packages: [1] "splines" "tools" "stats" "graphics" "grDevices" "utils" [7] "datasets" "methods" "base" other attached packages: exonmap plier RMySQL DBI RColorBrewer simpleaffy "1.0.06" "1.6.0" "0.6-0" "0.2-3" "0.2-3" "2.10.31" genefilter survival affy affyio Biobase "1.14.1" "2.32" "1.14.2" "1.4.0" "1.14.1" > $ mysqladmin version mysqladmin Ver 8.41 Distrib 5.0.45, for unknown-linux-gnu on ia64 _______________________________________________________________ Tore Eriksson [tore.eriksson ad po.rd.taisho.co.jp]
Survival genefilter affy plier affyio exonmap Survival genefilter affy plier affyio • 1.2k views
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@michal-okoniewski-1752
Last seen 10.2 years ago
Hi Tore, I cannot reproduce your results with my exonmap - in all the cases (except the first one of course) I get the same list of 12 exons. Your problem looks as if the result set is randomly truncated without producing any error. We have seen problems with translation function when the Ensembl database was corrupted, but it did not look exactly like that.. Could you please let me know if your results are reproducible in time and between R sessions? Cheers, Michal -----Original Message----- From: Tore@mail02.rd.taisyo.co.jp [mailto:Tore@mail02.rd.taisyo.co.jp] On Behalf Of Tore Eriksson Sent: 27 August 2007 01:32 To: bioconductor at stat.math.ethz.ch Subject: Exonmap mapping problems Hello everybody! I have encountered some strange behaviour when using the mapping functions in the exonmap package. The results are inconsistent for different length inputs, and for long lists there is no result at all. Some examples and the sessionInfo follows below. Shown are results for probest.to.exon, but probeset.to.gene gives similar results. Any tips are most welcome. Tore > xmapDatabase("Human") Switching to human database... done. > length(sigs) [1] 1865 > probeset.to.exon(sigs, debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece NULL > sigs[1:14] [1] "2315924" "2316106" "2318791" "2319627" "2320571" "2320764" "2321153" [8] "2321396" "2322705" "2323289" "2326877" "2328133" "2330669" "2331628" > probeset.to.exon(sigs[1:9], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" "ENSE00001400447" "ENSE00001422373" "ENSE00001469531" [9] "ENSE00001469483" "ENSE00001424556" "ENSE00001469369" "ENSE00001374956" > probeset.to.exon(sigs[1:10], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece NULL > probeset.to.exon(sigs[2:10], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" "ENSE00001400447" "ENSE00001422373" "ENSE00001469531" [9] "ENSE00001469483" "ENSE00001424556" "ENSE00001469369" "ENSE00001374956" > probeset.to.exon(sigs[2:11], debug=6) elt.size 7 list.size 8125 num.lists 0 extrabit 1 Processing 1 th piece [1] "ENSE00001478357" "ENSE00001478400" "ENSE00001370617" "ENSE00001478362" [5] "ENSE00000862165" > sessionInfo() R version 2.5.0 (2007-04-23) ia64-unknown-linux-gnu locale: LC_CTYPE=ja_JP.UTF-8;LC_NUMERIC=C;LC_TIME=C;LC_COLLATE=C;LC_MONETARY=C ;L C_MESSAGES=C;LC_PAPER=C;LC_NAME=C;LC_ADD RESS=C;LC_TELEPHONE=C;LC_MEASUREMENT=C;LC_IDENTIFICATION=C attached base packages: [1] "splines" "tools" "stats" "graphics" "grDevices" "utils" [7] "datasets" "methods" "base" other attached packages: exonmap plier RMySQL DBI RColorBrewer simpleaffy "1.0.06" "1.6.0" "0.6-0" "0.2-3" "0.2-3" "2.10.31" genefilter survival affy affyio Biobase "1.14.1" "2.32" "1.14.2" "1.4.0" "1.14.1" > $ mysqladmin version mysqladmin Ver 8.41 Distrib 5.0.45, for unknown-linux-gnu on ia64 _______________________________________________________________ Tore Eriksson [tore.eriksson ad po.rd.taisho.co.jp] -------------------------------------------------------- This email is confidential and intended solely for the use o...{{dropped}}
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