Hi, I'm using R 2.5.0 on openSUSE 10.2 x86_64 with biocLite packages. I started by creating the TargetInfo and probe related information objects in marray. I then realized that the read.Agilent function did this automatically and proceeded to create the marrayRaw class. This seems to have worked fine for the 3* 44k arrays I'm working on. I am now working on 2*244k Agilent arrays. Using the same function I am not been given any errors in R but my computer seems to slow but doesn't crash when reading in the flat text files from the arrays. I am leaving it for 20 mins or so. Is there a problem with the package due to the size of the arrays or could it be a problem with my system? Thanks for your help. Regards John