We are offering 2 positions for scientific programmers with a strong background in Bio- and Chemoinformatics, Data Mining, Toxicology and (Q)SAR modelling. The successful candidates will design, implement and test open source software for the EU projects Sens-it-iv www.sens-it-iv.eu) and OpenTox www.opentox.org) using Ruby (on rails) as the main scripting language and a variety of external software packages, libraries and custom developments for problem specific tasks (e.g. Bioconductor/R for Bioinformatics/Data Mining, OpenBabel/CDK for Chemoinformatics, lazar for toxicity predictions, ...). We expect efficient, independent and goal-oriented programming skills, a familarity with open source development procedures and the ability to translate life-science concepts into algorithms (and vice versa). We offer a congenial working atmosphere in a small group with close international collaborations and ample room to pursue your scientific interests. The salary will follow the german (E13/BAT-IIA) scheme, and the positions are initially limited to the duration of the EU projects (3 years). Please send a brief CV with a description of your scientific background and a summary of your programming experience by email to helma at in- silico.de, if you are interested in one of these positions (Deadline: October 31). Christoph Helma == Freiburger Zentrum f. Datenanalyse u. Modellbildung (FDM) Brief description of the EU projects: The Sens-it-iv project aims to develop new in vitro techniques for the detection of allergenic effects, our group maintains the internal database (mainly toxicogenomics, -proteomics and -metabolomics data) as well as data mining facilities. OpenTox will create an open source framework for predictive toxicology with a database backend, facilities for automated QSAR model development and validation, a plug-in system for novel data mining and QSAR algorithms and an easy-to-use web interface for end-users.