Senior Bioinformatics Research Scientist http://www.garvan.org.au/pdfs/jobs/Senior%20Bioinformatics%20Research% 20Officer%20Dec07.pdf The Epigenetics Group in the Cancer Program in collaboration with the Peter Wills Bioinformatics Centre at the Garvan Institute of Medical Research, seek a fulltime Senior Bioinformatics Research Officer to perform epigenomic analyses including DNA methylation, chromatin modification and micro RNA genome array studies. The major goal will be to initiate and develop a range of novel large scale epigenome analyses to identify new epigenetic lesions, in particular in breast and prostate cancer. The Garvan Institute is actively engaged in medical research into major human diseases involving molecular, cellular, genetic and clinical research. The Cancer Research Program is an integrated series of strongly interactive Research Groups undertaking research aimed at increasing the international knowledge base on the development, progression, treatment and prevention of human cancers. The current emphasis of the epigenetic laboratory centres on developing a deeper understanding of the mechanism responsible for aberrant DNA methylation and chromatin remodelling in cancer. We are seeking an individual with a PhD who has preferably had experience in whole genome wide array analyses, in particular ChIP on chip tiling arrays. Candidates will have a strong background in multi-univariate and Bayesian statistics, and experience in machine-learning techniques. Knowledge of the R programming language and experience with Gene Set Enrichment Analysis are desirable. The successful applicant will also be given freedom and encouragement to further develop statistical techniques for data analysis and will be actively involved in specific scientific research projects within the Epigenetics group. The successful applicant will be required to interact closely with phD students and postdoctoral scientists to ensure an active and vibrant Epigenetic Research Program. The successful applicant will report to the head of the Epigenetics group, A/Prof Susan Clark. The position is a full-time fixed term appointment for 24 months in the first instance with renewal subject to suitability. Written applications including a cover letter, Curriculum Vitae, academic transcript and contact details of three professional referees, should be forwarded to hr at garvan.org.au, or mailed to the address below. Human Resource Manager Garvan Institute of Medical Research 384 Victoria Street, Darlinghurst, NSW, 2010 Fax: (02) 9295 8151 Email: hr at garvan.org.au Closing Date for Applications: 30th January 2007