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Hi Anne, You need to normalize your data separately. Please refer to this really recent thread: https://stat.ethz.ch/pipermail/bioconductor/2008-April/022062.html Regarding you memory problem have a look at justGCRMA or justRMA and the various option for memory optimization they provide. running justGCRMA on your data should run just fine and eat less than 2Gb RAM. David On Apr 25, 2008, at 1:58 PM, Anne wrote: > Hi, > > I need to combine a set of HGU133a2 (68) and HGU133plus2 (57) chips. > Found > the package matchprobes to be usefull for this purpose.... but since > I have > to load my data by the read.affybatch function it takes up to much > memory > just to do this part. > > Any smart short cut to avoid this memory problem? > > best regards > Anne > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at stat.math.ethz.ch > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor