Dear list, I am trying to create Arabidopsis mappings from genes to Pfam- profiles, because these are not included in the default annotation package. Thus I have downloaded the mappings from IPI and generated a table with column1 the gene id and column 2 the Pfam profiles, and dropped this table into a SQLite-file (Pfam.sqlite) using the RSQLite package. In the end I would like to link this information to a normal annotation package for Arabidopsis but would also be happy to generate a separate Pfam- Annotation package only. My first approach using the makeAnnDbPkg failed due to an error (see below) Any suggestions? >myPath <- getwd() > seed <- new("AnnDbPkgSeed", Package="ATHPfam", Version="1.0", AnnObjPrefix="ATHPfam") > makeAnnDbPkg(seed, dbfile="Pfam.sqlite", dest_dir=myPath, no.man=TRUE) Error in sqliteExecStatement(con, statement, bind.data) : RS-DBI driver: (error in statement: no such table: metadata) > sessionInfo() R version 2.7.0 (2008-04-22) i386-apple-darwin8.10.1 locale: en_IE.UTF-8/en_IE.UTF-8/C/C/en_IE.UTF-8/en_IE.UTF-8 attached base packages: [1] tools stats graphics grDevices utils datasets methods base other attached packages: [1] AnnotationDbi_1.2.0 Biobase_2.0.1 RSQLite_0.6-8 DBI_0.2-4 [[alternative HTML version deleted]]