Hi, I have 12 dye-swap design microarrays for 6 samples, which means each sample has 2 microarrays with dye swap, and we did the analysis using R limma package. When I submit the paper, the database asked for normalized data per each sample (biological replicate) for dye-swap experiment. But I only can get normalized data for each slide, and I have two slides per sample. I don't know how to get a single M value for each biological replicate. Can somebody help me figure out this issue? Thank you so much! Fei [[alternative HTML version deleted]]