Hi All, I've just updated from R-1.7.1 to R-1.8.0 on my linux machine. I've successfully updated all contributed R packages via update.packages(), but the Bioconductor packages failed (see below). Any idea what's going wrong? Are the repositories still down? Even with method="wget" is does not work. I've to use a proxy with authentification, and I've setup a .wgetrc and a .Rprofile, so that the download.file uses wget, and I don't have any problems using wget from the commandline. kind regards, Arne > update.packages2() Note: argument `lib' is missing: using /tgx/soft/lib/R/library Warning message: cannot open: HTTP status was `407 Proxy Authorization Required' Note: http://www.bioconductor.org/CRANrepository does not seem to have a valid repository, skipping Warning message: cannot open: HTTP status was `407 Proxy Authorization Required' Note: http://www.bioconductor.org/repository/release1.2/package does not seem to have a valid repository, skipping Warning message: cannot open: HTTP status was `407 Proxy Authorization Required' Note: http://www.bioconductor.org/repository/devel/package does not seem to have a valid repository, skipping Warning message: cannot open: HTTP status was `407 Proxy Authorization Required' Note: http://www.bioconductor.org/data/dataRepos does not seem to have a valid repository, skipping Warning message: cannot open: HTTP status was `407 Proxy Authorization Required' Note: http://www.bioconductor.org/repository/Courses does not seem to have a valid repository, skipping Error in update.packages2() : No repositories to search