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mcoyne@boninc.com
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@mcoyneboninccom-3525
Last seen 10.3 years ago
BODY { font-family:Arial, Helvetica, sans-serif;font-size:12px; }Hi
All,
In the paper Exploration, normallization, and genotype calls of
high-density oligonucleotide SNP array data, Benilton Carvalho, Henrik
Bengtsson, Terrence Speed, Rafael Irizarry; it says: " Our methodology
makes no use of the MM features mainly because we see a trend in the
company no longer to use this type
of probe. Note that an array with no MMs can accommodate features
for twice as many SNPs."
I happened to read another paper on BMC Bioinformatics, Feb 2009,
Genotype and inflated type I error rate in genome-wide association
case/contronl studies, Joshua Sampson and Hongyu Zhao, in Table 1,
page 3, indicates CRLMM "indicates use of mismatched probes"
Would someone comment whether or not CRLMM is MM idependent?
Thank you
Kind Regards,
My Coyne
mcoyne@boninc.com
(cel): 301-399-6351
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