Please advise me how to fix this problem. I loaded R - 1.8.0 to my pc (Windows 2000) then ran source("http://www.bioconductor.org/getBioC.R") getBioC(relLevel="devel") from R window, I typed : library(affy) then I got : > library(affy) Welcome to Bioconductor Vignettes contain introductory material. To view, simply type: openVignette() For details on reading vignettes, see the openVignette help page. Error in setMethod("sampleNames", "Cel", function(object) object@name, : No existing definition for function "sampleNames" Error in library(affy) : .First.lib failed So, I tried to update pacakages: update.packages2("affy") Then I ran again, but got the following error. > library(affy) Error in bindingIsLocked(m1, where) : not an environment Error in setClass("AffyBatch", representation(cdfName = "character", nrow = "numeric", : Error in contained classes ("exprSet") for class "AffyBatch"; class definition removed from "affy" Error in library(affy) : .First.lib failed Can someone tell what is wrong? It looks like I should not update package, but it still had an error in setMethod function. Thanks yasushi [[alternative HTML version deleted]]