Does any one know how to calculate the BOOTSTRAP-adjusted p-values. The normalized expression values are in the 22283-by-16 matrix expr. The 16-long dclass vector contains the classifiers [0 1 0 1 0 1 0 ...] The goal is to compute the 22283-long vector with the adjusted p-values. Does any one have expericence with boot() or another procedure? Thank you for your help.

If you are simply looking to calculate some permutation adjusted p-values, you should look at the help for either multtest or siggenes. Both packages have very clear help pages. I am not sure how (or why) you want to bootstrap your data, but if you really want to do this, you are going to have to figure it out on your own because there are no 'canned' functions to do what you want. I would recommend using either multtest or siggenes. HTH, Jim James W. MacDonald Affymetrix and cDNA Microarray Core University of Michigan Cancer Center 1500 E. Medical Center Drive 7410 CCGC Ann Arbor MI 48109 734-647-5623 >>> "Kevin Dawson" <kdawson@ucdavis.edu> 12/07/03 07:02PM >>> Does any one know how to calculate the BOOTSTRAP-adjusted p-values. The normalized expression values are in the 22283-by-16 matrix expr. The 16-long dclass vector contains the classifiers [0 1 0 1 0 1 0 ...] The goal is to compute the 22283-long vector with the adjusted p-values. Does any one have expericence with boot() or another procedure? Thank you for your help. _______________________________________________ Bioconductor mailing list Bioconductor@stat.math.ethz.ch https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor