Many emails are about this or that does not work, but I have run maanova many, many times with BioC and various Macs. Runs are long, longest about 30 hours. While running I use the Macs for other stuff with some trepidation thinking, oh dear, at finish minus 1hr something will crash and I will need to start over. Such has never happened, all runs have finished. Thanks to the R BioC R.app Mac persons for making such possible. [[alternative HTML version deleted]]