Hello, I constructed a methyLumiSet for my data, and then tried to apply the normalization upon it: normalizeMethyLumiSet(eset) But I get an error: Fehler in if (newcy5l < cy3l) { : Fehlender Wert, wo TRUE/FALSE nötig ist (translation: error in if (newcy5l < cy3l) { : missing value, where TRUE/FALSE is necessary) Would be greatefull for a hint on what the cause of this message could be. Is it may be because I have no cy5, cy3 labelings within my data (instead I have methylated, unmethylated -labels) below the session-info. best, Noemi R version 2.10.0 (2009-10-26) i386-pc-mingw32 locale: [1] LC_COLLATE=German_Germany.1252 LC_CTYPE=German_Germany.1252 [3] LC_MONETARY=German_Germany.1252 LC_NUMERIC=C [5] LC_TIME=German_Germany.1252 attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] limma_3.2.3 methylumi_1.0.0 Biobase_2.6.1 loaded via a namespace (and not attached): [1] grid_2.10.0 lattice_0.17-26 tools_2.10.0 [[alternative HTML version deleted]]