Dear all, i need to ask two quections which are in my mind, 1.Wether lowess normalization take in yo account of dye bayes during normalization? 2.How density plots are drawn from MA objects (i.e, after lowess normalization) as it contains only M and A values not R and G values, to draw red and green line(peaks) on the plot? -- Veerendra. [[alternative HTML version deleted]]

Hi Veerendra, On 8/29/2010 11:39 PM, Veerendra GP wrote: > Dear all, > i need to ask two quections which are in my mind, > 1.Wether lowess normalization take in yo account of dye bayes during > normalization? That is the intent of a loess normalization. > 2.How density plots are drawn from MA objects (i.e, after lowess > normalization) as it contains only M and A values not R and G values, to > draw red and green line(peaks) > on the plot? If you have both the M and A values, it is simple algebra to compute the R and G values. Best, Jim -- James W. MacDonald, M.S. Biostatistician Douglas Lab University of Michigan Department of Human Genetics 5912 Buhl 1241 E. Catherine St. Ann Arbor MI 48109-5618 734-615-7826 ********************************************************** Electronic Mail is not secure, may not be read every day, and should not be used for urgent or sensitive issues