recently tried to use ReadAffy fucntion for some CEL files and received: > Data <- ReadAffy() Error in read.affybatch(filenames = filenames, phenoData = phenoData, : The file /cool/delta_microarray/YZ04022501.CEL does not look like a CEL file most likely because the CEL file is binary. found an old thread for bioconductor which said the newest affy devel package can handle binary files and runs in R 1.8.1. however when i try: > getBioC(libName="affy", relLevel="devel") Running getBioC version 1.2.52.... If you encounter problems, first make sure that you are running the latest version of getBioC() which can be found at: www.bioconductor.org/getBioC.R Please direct any concerns or questions to bioconductor@stat.math.ethz.ch. Error in getBioC(libName = "affy", relLevel = "devel") : You are currently running R version 1.8.1, however R version 1.9.0 is required. am i doing something wrong here?? For anyone else having this problem i found a work around. go to: http://www.affymetrix.com/support/developer/tools/affytools.affx there is a program here that will convert binary to ASCII and vise versa on a windows machine. -isaac --