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khadeeja ismail
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@khadeeja-ismail-4711
Last seen 8.2 years ago
Dear All,
I have a small problem that is silimar to the case below, and would
really appreciate if someone could give me some ideas.
I am doing a pairwise analysis for some samples (say 8 pairs, A1, A2,
B1, B2, C1, C2,...H1, H2) using linear models, to find out gene
expression difference between before treatment and after treatment.
But if the length of the treatment is different for every pair, how
can I include the treatment length in my analysis?
If one objective of my study is to see if the difference in gene
expression correlates with the treatment length, will adjusting the
expression differences relative to the highest treatment length
introduce a bias?
Thanks in advance,
Hajja
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