I am using illuminaHumanv4.db for my research, so first of all, thank you for maintaining this very valuable package! When working with the illuminaHumanv4listNewMappings, I realised that some genomic coordinates are separated with " " instead of ",". Almost all other multiple entries are separated with a ",". Additionlly, genomic position of those entries does not seem to match with ucsc hg19 browser: require(illuminaHumanv4.db) test <- illuminaHumanv4fullReannotation() str(test) grep(" ", test$GenomicLocation, value=T) [1] "chr9:70645819:70645844:+ chr9:68298969:68298994:+ chr9:42251008:42251033:+ chr9:45442520:45442545:+" [2] "chr19:53832784:53832812:+ chr19:53268654:53268682:+" [3] "chr7:142008849:142008868:+ chr1:161139601:161139616:+" [4] "chr7:142008849:142008868:+ chr1:161139601:161139616:+" [5] "chrX:71034915:71034941:+ chrX:70888863:70888889:+ chrX:70885403:70885429:+" [6] "chrX:71034915:71034941:+ chrX:70888863:70888889:+ chrX:70885403:70885429:+" [7] "chr22:18979472:18979497:+ chrX:70888863:70888889:+ chrX:70885403:70885429:+" [8] "chr1:149906516:149906531:+ chr1:185572746:185572761:+" [9] "chr1:176811981:176811996:+ chr1:161139601:161139616:+" Is there any specific reason for this? When looking on illuminaHumanv4.db_1.10.0, other probes were effected, but the problem appeared to be present, too. -- output of sessionInfo(): R version 2.14.0 (2011-10-31) Platform: i386-pc-mingw32/i386 (32-bit) locale: [1] LC_COLLATE=German_Germany.1252 LC_CTYPE=German_Germany.1252 [3] LC_MONETARY=German_Germany.1252 LC_NUMERIC=C [5] LC_TIME=German_Germany.1252 attached base packages: [1] stats graphics grDevices utils datasets methods base other attached packages: [1] illuminaHumanv4.db_1.12.1 org.Hs.eg.db_2.6.4 [3] RSQLite_0.10.0 DBI_0.2-5 [5] AnnotationDbi_1.16.5 Biobase_2.14.0 loaded via a namespace (and not attached): [1] IRanges_1.12.3 -- Sent via the guest posting facility at bioconductor.org.