Dear Bo, > Date: Tue, 24 Apr 2012 02:06:56 +0200 > From: bburla at botinst.uzh.ch > To: bioconductor at r-project.org > Subject: [BioC] Array weights in the 'removeBatchEffect' function? > > Dear List > > Is it possible to correct expression values for array weights (obtained > via the arrayWeights function) using the removeBatchEffect function? No. > Or is there any other way to obtain expression values corrected for > array weights, No. It is not theoretically possible. In principle, one could adjust fold changes for array weights, but not expression values themselves. > in order to create heatmaps or conducting clustering analyses? In principle, plotMDS() in the limma package could take account of array weights, but at the moment it doesn't. Best wishes Gordon > Thank you very much for your help. > Bo > ------------------ > B. Burla > University of Zurich > Zurich > Switzerland ______________________________________________________________________ The information in this email is confidential and intend...{{dropped:4}}