Hello, is there an easy way to use the GOrilla algorithm in R? (http://www.biomedcentral.com/1471-2105/10/48) It allows to find significant enrichment in an ordered list rather than by comparing two groups (DE vs background as most of enrichment analysis algorithms use). Best regards, j. -- -------- Dr. January Weiner 3 -------------------------------------- Max Planck Institute for Infection Biology Charit?platz 1 D-10117 Berlin, Germany Web : www.mpiib-berlin.mpg.de Tel : +49-30-28460514 Fax : +49-30-28450505