Hi, I have been trying to compute hazard ratio between groups. I failed to find similar examples. I have data like this: status time group 1 LIVING 14 1 2 LIVING 44 5 3 DECEASED 32 4 4 LIVING 8 7 5 LIVING 19 4 6 LIVING 22 4 7 LIVING 63 6 8 LIVING 44 3 9 LIVING 25 3 10 LIVING 60 3 11 DECEASED 25 4 12 LIVING 62 2 13 LIVING 43 6 14 LIVING 42 6 15 LIVING 44 2 16 LIVING 21 4 17 LIVING 26 4 18 LIVING 25 4 19 LIVING 24 3 20 LIVING 16 1 I have successfully plotted kaplan meier curve for each group. Now I want to compute hazard ratio between the groups. The result could be like a symmetric matrix. Each entry Eij shows the hazard ratio between group i and group j. How can I do this? Please help me. Br, Luffy

This isn't a Bioconductor question. Please direct these sorts of questions to R-help. On 7/9/2012 7:08 AM, Farscape2012 wrote: > Hi, > > I have been trying to compute hazard ratio between groups. I failed to > find similar examples. > > I have data like this: > status time group > 1 LIVING 14 1 > 2 LIVING 44 5 > 3 DECEASED 32 4 > 4 LIVING 8 7 > 5 LIVING 19 4 > 6 LIVING 22 4 > 7 LIVING 63 6 > 8 LIVING 44 3 > 9 LIVING 25 3 > 10 LIVING 60 3 > 11 DECEASED 25 4 > 12 LIVING 62 2 > 13 LIVING 43 6 > 14 LIVING 42 6 > 15 LIVING 44 2 > 16 LIVING 21 4 > 17 LIVING 26 4 > 18 LIVING 25 4 > 19 LIVING 24 3 > 20 LIVING 16 1 > > I have successfully plotted kaplan meier curve for each group. Now I > want to compute hazard ratio between the groups. The result could be > like a symmetric matrix. Each entry Eij shows the hazard ratio > between group i and group j. > > How can I do this? Please help me. > > Br, > Luffy > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor -- James W. MacDonald, M.S. Biostatistician University of Washington Environmental and Occupational Health Sciences 4225 Roosevelt Way NE, # 100 Seattle WA 98105-6099

Hi Luffy, I recently had to generate HR's and KM plots. I used the survival package - which is what is used for KM plots but it can also get you Hazard ratios, look at the function: summary.coxph() or coxph then summary of that. HTH, Natasha -----Original Message----- From: bioconductor-bounces@r-project.org [mailto:bioconductor- bounces@r-project.org] On Behalf Of Farscape2012 Sent: 09 July 2012 12:08 To: bioconductor at r-project.org Subject: [BioC] Survival analysis (hazard ratio calculation) Hi, I have been trying to compute hazard ratio between groups. I failed to find similar examples. I have data like this: status time group 1 LIVING 14 1 2 LIVING 44 5 3 DECEASED 32 4 4 LIVING 8 7 5 LIVING 19 4 6 LIVING 22 4 7 LIVING 63 6 8 LIVING 44 3 9 LIVING 25 3 10 LIVING 60 3 11 DECEASED 25 4 12 LIVING 62 2 13 LIVING 43 6 14 LIVING 42 6 15 LIVING 44 2 16 LIVING 21 4 17 LIVING 26 4 18 LIVING 25 4 19 LIVING 24 3 20 LIVING 16 1 I have successfully plotted kaplan meier curve for each group. Now I want to compute hazard ratio between the groups. The result could be like a symmetric matrix. Each entry Eij shows the hazard ratio between group i and group j. How can I do this? Please help me. Br, Luffy _______________________________________________ Bioconductor mailing list Bioconductor at r-project.org https://stat.ethz.ch/mailman/listinfo/bioconductor Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor