Hi! I'm trying to find motifs in a file of 50 sequences in FASTA format, they are particular in that they have no "G" so when I run this: >library(cosmo) > seqal <- system.file("Exfiles/short702k.FASTA", package="cosmo") > res <- cosmo(seqs=seqal, constraints="None", minW=10, maxW=10, models="TCM") I get the message: new Irange 202 is greater than pre-calculated Irange 0. numSites = 2. Exiting. If I add only one ficticious G in one of the sequences then it works, but I get some G's in the seqlogo plot Ana -- output of sessionInfo(): new Irange 202 is greater than pre-calculated Irange 0. numSites = 2. Exiting. -- Sent via the guest posting facility at bioconductor.org.