Thanks Kasper, Just reinstalled sva, Matric and mgcv through biocLite (like I always do to avoid 'mixing' problems), but this didn't solve the problem... Since it otherwise will get too complicated I just consider this as a good reason to update to the latest R version (2.15.2). Guido -----Original Message----- From: Kasper Daniel Hansen [mailto:kasperdanielhansen@gmail.com] Sent: Tuesday, November 20, 2012 17:52 To: Hooiveld, Guido Cc: bioconductor at r-project.org Subject: Re: [BioC] SVA: problem loading on Windows You seem to have a problem with the Matrix package and the mgcv package. Both of these ship with R, so I would guess this is indicative of a (big) problem with your R installation - you seem to be mixing packages from slightly different versions of R. You could try re-installing your packages. This really has nothing to do with sva. Kasper On Tue, Nov 20, 2012 at 11:08 AM, Hooiveld, Guido <guido.hooiveld at="" wur.nl=""> wrote: > Hi, > I would like to load the library SVA but run into problems. The reported error message is too cryptic to me, so I would appreciate if someone could give a hint on how to solve it. As far as I know all dependencies are installed on my machine. > Note that I never experienced this type of error before, also not when loading SVA (in previous versions of R). > > Thanks, > Guido > >> library(sva) > Loading required package: corpcor > Loading required package: mgcv > Error in inDL(x, as.logical(local), as.logical(now), ...) : > unable to load shared object 'C:/Program Files/R/R-2.15.1/library/Matrix/libs/i386/Matrix.dll': > LoadLibrary failure: The specified procedure could not be found. > > In addition: Warning message: > package 'mgcv' was built under R version 2.15.2 > Error: package 'mgcv' could not be loaded >> sessionInfo() > R version 2.15.1 (2012-06-22) > Platform: i386-pc-mingw32/i386 (32-bit) > > locale: > [1] LC_COLLATE=English_United States.1252 LC_CTYPE=English_United States.1252 LC_MONETARY=English_United States.1252 > [4] LC_NUMERIC=C LC_TIME=English_United States.1252 > > attached base packages: > [1] stats graphics grDevices utils datasets methods base > > other attached packages: > [1] corpcor_1.6.4 > > loaded via a namespace (and not attached): > [1] grid_2.15.1 lattice_0.20-10 nlme_3.1-105 >> > > > --------------------------------------------------------- > Guido Hooiveld, PhD > Nutrition, Metabolism & Genomics Group Division of Human Nutrition > Wageningen University Biotechnion, Bomenweg 2 > NL-6703 HD Wageningen > the Netherlands > tel: (+)31 317 485788 > fax: (+)31 317 483342 > email: guido.hooiveld at wur.nl > internet: http://nutrigene.4t.com > http://scholar.google.com/citations?user=qFHaMnoAAAAJ > http://www.researcherid.com/rid/F-4912-2010 > > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor