http://www.bioconductor.org/packages//2.10/data/annotation/manuals/KEG G.db/man/KEGG.db.pdf Hi, I read the documentation from the above link to see if there is any tool that can convert GO annotations to Enzyme Commission numbers automatically. I went through the file at http:/www.geneontology.org/mapping/ec2go I have a big file which contains GO Annotations and my objective is to convert those GO Annotations to Enzyme Commission numbers for further analysis. I would like to check if KEGG.db will be able to do this GO to Enzyme commission number conversion. Thanks. Priya -- output of sessionInfo(): Examples xx <- as.list(KEGGGO2ENZYMEID) if(length(xx) > 0){ # Get the value of the first key xx[[1]] # Get values for a few keys if(length(xx) >= 3){ xx[1:3] } } This is the R code that is available. -- Sent via the guest posting facility at bioconductor.org.