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Last seen 10.3 years ago
Dear all,
Is there any way to get all entrez identifiers that are annotated with
KEGG pathways? Actually I am using GOStats package in R to perform
KEGG pathway enrichment analysis.. In general, for each KEGG pathway
term there is a list of annotated hgnc symbols or entrez identifiers..
For all KEGG pathway terms we must have one list of entrez
identifiers. I want to have that list...
What I am doing write now is as follows:
library(biomaRt)
library("GO.db")
library("KEGG.db")
library("GOstats")
library("hgu133plus2.db")
library("EMA")
library("fdrtool")
library("org.Hs.eg.db")
ensembl = useMart("ensembl", dataset = "hsapiens_gene_ensembl")
x <- hgu133plus2PATH
mapped_probes <- mappedkeys(x)
b<-getBM(attributes=c("hgnc_symbol"),filters="affy_hg_u133_plus_2",val
ues=mapped_probes,mart=ensembl)
Is it the correct way to do that?
Thanks in advance.. :)
-- output of sessionInfo():
R version 2.15.1 (2012-06-22)
Platform: x86_64-pc-linux-gnu (64-bit)
locale:
[1] LC_CTYPE=en_US.UTF-8 LC_NUMERIC=C
[3] LC_TIME=en_US.UTF-8 LC_COLLATE=en_US.UTF-8
[5] LC_MONETARY=en_US.UTF-8 LC_MESSAGES=en_US.UTF-8
[7] LC_PAPER=C LC_NAME=C
[9] LC_ADDRESS=C LC_TELEPHONE=C
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C
attached base packages:
[1] stats graphics grDevices utils datasets methods base
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