Gene symbol update.
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Jinyan Huang ▴ 110
@jinyan-huang-5828
Last seen 10.3 years ago
Dear expert, Is there some bioconductor package to update Gene symbol ? e.g. CRSP6 update to MED17. http://www.ncbi.nlm.nih.gov.ezp-prod1.hul.harvard.edu/gene/9440 KIAA0804 update to VPS8 http://www.ncbi.nlm.nih.gov.ezp- prod1.hul.harvard.edu/gene/?term=KIAA0804 -- Best wishes, Jinyan HUANG
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Marc Carlson ★ 7.2k
@marc-carlson-2264
Last seen 8.4 years ago
United States
Hi Jinyan, It depends. It depends on what you are using for annotations, and also which version of bioconductor/R you are using. If you are using packages from the release last fall for example, then those things will have been updated back then. We are currently in the middle of updating these things right now for the upcoming spring release. And if you are using a web service like biomaRt, things may have already been updated very recently. So it depends on what you are using for annotations... Unless maybe you are actually asking about what to do with a list of old gene symbols that you simply want to modernize. In that case, I think you want do do something like this: library(org.Hs.eg.db) select(org.Hs.eg.db, keys = c("CRSP6","KIAA0804"), cols="SYMBOL", keytype="ALIAS") Hope this helps, Marc On 03/14/2013 10:09 PM, Jinyan Huang wrote: > Dear expert, > > Is there some bioconductor package to update Gene symbol ? > > e.g. > CRSP6 update to MED17. > http://www.ncbi.nlm.nih.gov.ezp-prod1.hul.harvard.edu/gene/9440 > > KIAA0804 update to VPS8 > http://www.ncbi.nlm.nih.gov.ezp- prod1.hul.harvard.edu/gene/?term=KIAA0804 > > -- > Best wishes, > > Jinyan HUANG > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor
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Marc? Thank you very much for you help. You reply really make sense to me. I have a list of old gene symbols that I simply want to modernize. You code is what I want. On Fri, Mar 15, 2013 at 8:32 PM, Marc Carlson <mcarlson at="" fhcrc.org=""> wrote: > Hi Jinyan, > > It depends. It depends on what you are using for annotations, and also > which version of bioconductor/R you are using. If you are using packages > from the release last fall for example, then those things will have been > updated back then. We are currently in the middle of updating these things > right now for the upcoming spring release. And if you are using a web > service like biomaRt, things may have already been updated very recently. > So it depends on what you are using for annotations... > > Unless maybe you are actually asking about what to do with a list of old > gene symbols that you simply want to modernize. In that case, I think you > want do do something like this: > > library(org.Hs.eg.db) > select(org.Hs.eg.db, keys = c("CRSP6","KIAA0804"), cols="SYMBOL", > keytype="ALIAS") > > Hope this helps, > > > Marc > > > > On 03/14/2013 10:09 PM, Jinyan Huang wrote: >> >> Dear expert, >> >> Is there some bioconductor package to update Gene symbol ? >> >> e.g. >> CRSP6 update to MED17. >> http://www.ncbi.nlm.nih.gov.ezp-prod1.hul.harvard.edu/gene/9440 >> >> KIAA0804 update to VPS8 >> http://www.ncbi.nlm.nih.gov.ezp- prod1.hul.harvard.edu/gene/?term=KIAA0804 >> >> -- >> Best wishes, >> >> Jinyan HUANG >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor at r-project.org >> https://stat.ethz.ch/mailman/listinfo/bioconductor >> Search the archives: >> http://news.gmane.org/gmane.science.biology.informatics.conductor > > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor -- Best wishes, Jinyan HUANG
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Marc? A little problem. When I modernize old gene symbols, some of them are not exited. e.g. select(org.Hs.eg.db, keys = c("9-Mar","5_8S_rRNA","384D8-2"), cols="SYMBOL", keytype="ALIAS")$SYMBOL Error in .select(x, keys, cols, keytype, jointype = jointype) : keys must be of the same keytype as the actual keytype For these old gene symbols, I want to return the same. The output I hope are as follow. Because I have a long list. ALIAS SYMBOL 9-Mar 9-Mar 5_8S_rRNA 5_8S_rRNA 384D8-2 384D8-2 On Fri, Mar 15, 2013 at 11:00 PM, Jinyan Huang <jhuang at="" hsph.harvard.edu=""> wrote: > Marc? > > Thank you very much for you help. You reply really make sense to me. I > have a list of old gene symbols that I simply want to modernize. You > code is what I want. > > On Fri, Mar 15, 2013 at 8:32 PM, Marc Carlson <mcarlson at="" fhcrc.org=""> wrote: >> Hi Jinyan, >> >> It depends. It depends on what you are using for annotations, and also >> which version of bioconductor/R you are using. If you are using packages >> from the release last fall for example, then those things will have been >> updated back then. We are currently in the middle of updating these things >> right now for the upcoming spring release. And if you are using a web >> service like biomaRt, things may have already been updated very recently. >> So it depends on what you are using for annotations... >> >> Unless maybe you are actually asking about what to do with a list of old >> gene symbols that you simply want to modernize. In that case, I think you >> want do do something like this: >> >> library(org.Hs.eg.db) >> select(org.Hs.eg.db, keys = c("CRSP6","KIAA0804"), cols="SYMBOL", >> keytype="ALIAS") >> >> Hope this helps, >> >> >> Marc >> >> >> >> On 03/14/2013 10:09 PM, Jinyan Huang wrote: >>> >>> Dear expert, >>> >>> Is there some bioconductor package to update Gene symbol ? >>> >>> e.g. >>> CRSP6 update to MED17. >>> http://www.ncbi.nlm.nih.gov.ezp-prod1.hul.harvard.edu/gene/9440 >>> >>> KIAA0804 update to VPS8 >>> http://www.ncbi.nlm.nih.gov.ezp- prod1.hul.harvard.edu/gene/?term=KIAA0804 >>> >>> -- >>> Best wishes, >>> >>> Jinyan HUANG >>> >>> _______________________________________________ >>> Bioconductor mailing list >>> Bioconductor at r-project.org >>> https://stat.ethz.ch/mailman/listinfo/bioconductor >>> Search the archives: >>> http://news.gmane.org/gmane.science.biology.informatics.conductor >> >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor at r-project.org >> https://stat.ethz.ch/mailman/listinfo/bioconductor >> Search the archives: >> http://news.gmane.org/gmane.science.biology.informatics.conductor > > > > -- > Best wishes, > > Jinyan HUANG -- Best wishes, Jinyan HUANG
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