Dear all, I would like to run an old R script (R2.5) to combine some recent HGU133A and A2 arrays. When I try to read these new arrays with read.affybatch on R2.5 it crashes > sapply(list.celfiles("NEW_DATA/", full.names=TRUE), read.affybatch) Is NEW_DATA//BC13_ARN0186_s1h1_U133A2.CEL really a CEL file? tried reading as text, gzipped text, binary and gzipped binary. The same command works well on R2.15 ! However, my next step is to combine U133A and A2 arrays using >res<-combineAffyBatch(list(pool1,pool2),c("hgu133aprobe","hgu133a2pro be"), newcdf="comb") And I just saw that the combineAffyBatch function is no more supported. So does anyone has any idea : 1/ to fix the issu I have when I tried to read my CEL file under R2.5 2/ to give me an alternative to the combineAffyBatch function Thank you Regards Nicolas