Are you using a very old version of affy? You might try upgrading to the current release version, which has the ability to read binary files. HTH, Jim James W. MacDonald Affymetrix and cDNA Microarray Core University of Michigan Cancer Center 1500 E. Medical Center Drive 7410 CCGC Ann Arbor MI 48109 734-647-5623 >>> Feng He <fhe@ucsd.edu> 06/30/04 03:19PM >>> Hello everybody, I used to use the following statement to read in the affy CEL data: Data<-ReadAffy("a.CEL") But I couldn't read the data in for one case, and the data person told me that it is because the data was created using new expression scanner. Would you please let me know if you have met similar issue, and how to solve it. Thank you so much for your help! Feng _______________________________________________ Bioconductor mailing list Bioconductor@stat.math.ethz.ch https://www.stat.math.ethz.ch/mailman/listinfo/bioconductor