Pathway analysis for differentially expressed genes
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Guest User ★ 13k
@guest-user-4897
Last seen 10.2 years ago
Hi Bioconductor users, I am fairly new to bioconductor. I have been given some differentially expressed genes (181) and I need to find the pathway analysis. What kind of informations are needed for pathway analysis and which packages are the best to analyze it. Thank you very much for help in advance. Regards, -- output of sessionInfo(): -- Sent via the guest posting facility at bioconductor.org.
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Paul Shannon ▴ 470
@paul-shannon-5944
Last seen 2.5 years ago
United States
Being new to Bioconductor, you might be best served if you examined functional enrichment of your genes first. This will acquaint you with the virtues (and perils!) of enrichment analysis, and set the stage for a subsequent pathway analysis. The BioC package "topGO" is a good place to start: http://www.bioconductor.org/packages/2.12/bioc/html/topGO.html - Paul On Sep 5, 2013, at 7:59 AM, kaushal Raj Chaudhary [guest] wrote: > > Hi Bioconductor users, > > I am fairly new to bioconductor. I have been given some differentially expressed genes (181) and I need to find the pathway analysis. What kind of informations are needed for pathway analysis and which packages are the best to analyze it. Thank you very much for help in advance. > > Regards, > > -- output of sessionInfo(): > > > > -- > Sent via the guest posting facility at bioconductor.org. > > _______________________________________________ > Bioconductor mailing list > Bioconductor at r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor
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