Entering edit mode
Hi Daniel,
I can't reproduce this error.
It looks like your version of R and Bioconductor packages are out of
date. The current R version is 3.0.2 and VariantAnnotation is 1.8.2
(release) and 1.9.7 (devel). Help for updating is here,
http://www.bioconductor.org/install/
Let me know if you get the same error after updating and send a small
sample file if possible.
Thanks.
Valerie
On 10/24/2013 08:58 PM, Daniel Cameron [guest] wrote:
> readVcf fails to load VCF files where alternate alleles containing
breakends exist but no symbolic alleles. If any variant in the VCF
contains a symbolic alleles, then the VCF does load correctly
(including any breakend alleles - see example below).
>
>
> Reproduction steps:
>> library(VariantAnnotation)
>> readVcf("fail.vcf", "fake.fa")
> Error in .Call2("new_XString_from_CHARACTER", classname, x,
start(solved_SEW), :
> key 91 (char '[') not in lookup table
>> readVcf("success.vcf", "fake.fa")
>
> fail.vcf:
> ##fileformat=VCFv4.1
> ##INFO=<id=svtype,number=1,type=string,description="type of="" structural="" variant"="">
> ##ALT=<id=del,description="deletion">
> #CHROM POS ID REF ALT QUAL FILTER INFO
> 1 1 ref1 G G[1:2[ . PASS SVTYPE=BND
>
> success.vcf:
> ##fileformat=VCFv4.1
> ##INFO=<id=svtype,number=1,type=string,description="type of="" structural="" variant"="">
> ##ALT=<id=del,description="deletion">
> #CHROM POS ID REF ALT QUAL FILTER INFO
> 1 1 ref1 G G[1:2[ . PASS SVTYPE=BND
> 1 2 ref2 G . PASS SVTYPE=DEL
>
>
> -- output of sessionInfo():
>
> R version 2.15.2 (2012-10-26)
> Platform: x86_64-w64-mingw32/x64 (64-bit)
>
> locale:
> [1] LC_COLLATE=English_Australia.1252
LC_CTYPE=English_Australia.1252 LC_MONETARY=English_Australia.1252
> [4] LC_NUMERIC=C
LC_TIME=English_Australia.1252
>
> attached base packages:
> [1] stats graphics grDevices utils datasets methods base
>
> other attached packages:
> [1] VariantAnnotation_1.4.12 Rsamtools_1.10.2
Biostrings_2.26.3 GenomicRanges_1.10.7 IRanges_1.16.6
> [6] BiocGenerics_0.4.0
>
> loaded via a namespace (and not attached):
> [1] AnnotationDbi_1.20.7 Biobase_2.18.0 biomaRt_2.14.0
bitops_1.0-6 BSgenome_1.26.1
> [6] DBI_0.2-7 GenomicFeatures_1.10.2 parallel_2.15.2
RCurl_1.95-4.1 RSQLite_0.11.4
> [11] rtracklayer_1.18.2 stats4_2.15.2 tools_2.15.2
XML_3.98-1.1 zlibbioc_1.4.0
>
> --
> Sent via the guest posting facility at bioconductor.org.
>
. PASS SVTYPE=DEL >>> >>> >>> -- output of sessionInfo(): >>> >>> R version 2.15.2 (2012-10-26) >>> Platform: x86_64-w64-mingw32/x64 (64-bit) >>> >>> locale: >>> [1] LC_COLLATE=English_Australia.1252 LC_CTYPE=English_Australia.1252 >>> LC_MONETARY=English_Australia.1252 >>> [4] LC_NUMERIC=C LC_TIME=English_Australia.1252 >>> >>> attached base packages: >>> [1] stats graphics grDevices utils datasets methods base >>> >>> other attached packages: >>> [1] VariantAnnotation_1.4.12 Rsamtools_1.10.2 >>> Biostrings_2.26.3 GenomicRanges_1.10.7 IRanges_1.16.6 >>> [6] BiocGenerics_0.4.0 >>> >>> loaded via a namespace (and not attached): >>> [1] AnnotationDbi_1.20.7 Biobase_2.18.0 biomaRt_2.14.0 >>> bitops_1.0-6 BSgenome_1.26.1 >>> [6] DBI_0.2-7 GenomicFeatures_1.10.2 >>> parallel_2.15.2 RCurl_1.95-4.1 RSQLite_0.11.4 >>> [11] rtracklayer_1.18.2 stats4_2.15.2 tools_2.15.2 >>> XML_3.98-1.1 zlibbioc_1.4.0 >>> >>> -- >>> Sent via the guest posting facility at bioconductor.org. >>> >> > > > ______________________________________________________________________ > The information in this email is confidential and inte...{{dropped:6}}