Cross map two different probe set IDs
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Jerry Cholo ▴ 190
@jerry-cholo-6218
Last seen 10.2 years ago
Hi everyone, Please let me know if we could cross map two different probe set IDs using gene names. In other words, two different probe set IDs were matched if they would share same gene name. If so, I would like to know whether or not one gene (let’s call it “gene A”) can be located in different chromosome. If later is true how we could match two different probe set IDs using only gene names. Thank you. Jerry [[alternative HTML version deleted]]
probe probe • 1.1k views
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Tim Triche ★ 4.2k
@tim-triche-3561
Last seen 4.3 years ago
United States
could you provide a short piece of code showing what you are trying to accomplish? The "same gene on different chromosomes" part is confusing. It suggests you are looking for paralogous or orthologous transcripts across organisms, so a piece of code concretely implementing your idea would help. *He that would live in peace and at ease, * *Must not speak all he knows, nor judge all he sees.* Benjamin Franklin, Poor Richard's Almanack<http: archive.org="" details="" poorrichardsalma00franrich=""> On Thu, Nov 21, 2013 at 10:57 AM, Jerry Cholo <jerrycholo@gmail.com> wrote: > > > Hi everyone, > Please let me know if we could cross map two different probe set IDs using > gene names. In other words, two different probe set IDs were matched if > they would share same gene name. If so, I would like to know whether or > not one gene (let’s call it “gene A”) can be located in different > chromosome. If later is true how we could match two different probe set > IDs using only gene names. Thank you. > Jerry > > [[alternative HTML version deleted]] > > > _______________________________________________ > Bioconductor mailing list > Bioconductor@r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: > http://news.gmane.org/gmane.science.biology.informatics.conductor > > [[alternative HTML version deleted]]
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Thanks for your reply. Actually, I need to match two different probe set IDs from two different arrays within same family (human). For example hg-st array with hg-u133. If two IDs had a gene name, we can use one instead of the other. Thanks, Jerry On Thu, Nov 21, 2013 at 11:41 AM, Tim Triche, Jr. <tim.triche@gmail.com>wrote: > could you provide a short piece of code showing what you are trying to > accomplish? The "same gene on different chromosomes" part is confusing. > It suggests you are looking for paralogous or orthologous transcripts > across organisms, so a piece of code concretely implementing your idea > would help. > > > *He that would live in peace and at ease, * > *Must not speak all he knows, nor judge all he sees.* > > Benjamin Franklin, Poor Richard's Almanack<http: archive.org="" details="" poorrichardsalma00franrich=""> > > > On Thu, Nov 21, 2013 at 10:57 AM, Jerry Cholo <jerrycholo@gmail.com>wrote: > >> >> >> Hi everyone, >> Please let me know if we could cross map two different probe set IDs using >> gene names. In other words, two different probe set IDs were matched if >> they would share same gene name. If so, I would like to know whether or >> not one gene (let’s call it “gene A”) can be located in different >> chromosome. If later is true how we could match two different probe set >> IDs using only gene names. Thank you. >> Jerry >> >> [[alternative HTML version deleted]] >> >> >> _______________________________________________ >> Bioconductor mailing list >> Bioconductor@r-project.org >> https://stat.ethz.ch/mailman/listinfo/bioconductor >> Search the archives: >> http://news.gmane.org/gmane.science.biology.informatics.conductor >> >> > [[alternative HTML version deleted]]
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Hi Jerry, If you are doing this sort of thing that I now think you might be doing, then I think you should be careful. Sometimes platforms were designed to measure one gene and then later on it turns out the the gene is a little different (genome builds were moving targets for many old platforms). Also, if you use something like gene symbols to match up that is also a problem since those are not always unique (a single gene symbol can sometimes point to many different genes). So it's a good idea to use something more concrete like an entrez gene ID instead. But even when doing that, you may run into problems if the different array platforms were based on very different genome builds. And as if that weren't enough, similar kinds of probes are not guaranteed to always work perfectly, let alone equivalently. Marc On 11/21/2013 11:48 AM, Jerry Cholo wrote: > Thanks for your reply. Actually, I need to match two different probe set > IDs from two different arrays within same family (human). For example > hg-st array with hg-u133. If two IDs had a gene name, we can use one > instead of the other. Thanks, Jerry > > On Thu, Nov 21, 2013 at 11:41 AM, Tim Triche, Jr. <tim.triche@gmail.com>wrote: > >> could you provide a short piece of code showing what you are trying to >> accomplish? The "same gene on different chromosomes" part is confusing. >> It suggests you are looking for paralogous or orthologous transcripts >> across organisms, so a piece of code concretely implementing your idea >> would help. >> >> >> *He that would live in peace and at ease, * >> *Must not speak all he knows, nor judge all he sees.* >> >> Benjamin Franklin, Poor Richard's Almanack<http: archive.org="" details="" poorrichardsalma00franrich=""> >> >> >> On Thu, Nov 21, 2013 at 10:57 AM, Jerry Cholo <jerrycholo@gmail.com>wrote: >> >>> >>> Hi everyone, >>> Please let me know if we could cross map two different probe set IDs using >>> gene names. In other words, two different probe set IDs were matched if >>> they would share same gene name. If so, I would like to know whether or >>> not one gene (let's call it "gene A") can be located in different >>> chromosome. If later is true how we could match two different probe set >>> IDs using only gene names. Thank you. >>> Jerry >>> >>> [[alternative HTML version deleted]] >>> >>> >>> _______________________________________________ >>> Bioconductor mailing list >>> Bioconductor@r-project.org >>> https://stat.ethz.ch/mailman/listinfo/bioconductor >>> Search the archives: >>> http://news.gmane.org/gmane.science.biology.informatics.conductor >>> >>> > [[alternative HTML version deleted]] > > > > _______________________________________________ > Bioconductor mailing list > Bioconductor@r-project.org > https://stat.ethz.ch/mailman/listinfo/bioconductor > Search the archives: http://news.gmane.org/gmane.science.biology.informatics.conductor [[alternative HTML version deleted]]
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