Hi, On Thu, Nov 21, 2013 at 1:07 PM, Abhishek Pratap <apratap at="" sagebase.org=""> wrote: > just in case it was missed earlier..still trying to see if org.Hs.eg.db > could be used to find all the coding and non-coding genes. Have you tried monkeying around with it at all? There may be a super elegant way to do so, but you should also be able to cobble your own solution together in a number of ways. (1) Looking at the output from `cols(org.Hs.eg.db)` suggest that there is at least one column (UNIPROT) that can tell you protein info about <whatever>. (2) Another thing to think about is that you can query a TranscriptDb object to get coding exons only. Assuming you have the `Homo.sapiens` package, you can query the TxDb package that comes with it to get all the coding exons (`cdsBy`) for example then link transcript IDs to entrez ids in a number of ways. -steve -- Steve Lianoglou Computational Biologist Genentech