How to calculate Pearson coefficient between 2 genes in a group including 1500 genes?
1
0
Entering edit mode
xpzhang ▴ 90
@xpzhang-780
Last seen 10.3 years ago
Hello, I encountered a big difficult question now. I have a gene expression prifile, which incoulded 1500 gene and 20 treatment. I wanted to calculate the Pearson coefficient between any gene-pairs in the 1500 gene. Firstly, I tried to use SAS 6.12 to do it. But I found that SAS can not read the all data, and it can only read 15 rows data. I don't know which tools I could use. Could anyone tell me? Thank you very much! -- Xiaopeng ZHANG<xpzhang@genetics.ac.cn>
• 1.0k views
ADD COMMENT
0
Entering edit mode
Antoine Lucas ▴ 100
@antoine-lucas-1127
Last seen 10.3 years ago
On Tue, 01 Mar 2005 18:52:09 +0800 xpzhang <xpzhang@genetics.ac.cn> wrote: > Hello, > > I encountered a big difficult question now. I have a gene expression > prifile, which incoulded 1500 gene and 20 treatment. I wanted to > calculate the Pearson coefficient between any gene-pairs in the 1500 > gene. I think function Dist from package amap does this matrix library(amap) Dist(data,method="pearson") or Dist(t(data),method="pearson") > Firstly, I tried to use SAS 6.12 to do it. But I found that SAS can not > read the all data, and it can only read 15 rows data. Well, this surprise me ! are you sure that data are not corrupted ? Regards. Antoine Lucas. -- Antoine Lucas Centre de g?n?tique Mol?culaire, CNRS 91198 Gif sur Yvette Cedex Tel: (33)1 69 82 38 89 Fax: (33)1 69 82 38 77
ADD COMMENT
0
Entering edit mode
On Tue, Mar 01, 2005 at 11:06:09AM +0100, Antoine Lucas wrote: > On Tue, 01 Mar 2005 18:52:09 +0800 > xpzhang <xpzhang@genetics.ac.cn> wrote: > > > Firstly, I tried to use SAS 6.12 to do it. But I found that SAS can not > > read the all data, and it can only read 15 rows data. > > Well, this surprise me ! are you sure that data are not corrupted ? This cannot be true. You must do something wrongg - at least if the problem is reading the data. I do not know how you calculate the paired correlations, so I guess you could run into a memory problem (although I find that highly unlikely). Not that I want you to use SAS of course :) -- Kasper Daniel Hansen, Research Assistant Department of Biostatistics, University of Copenhagen
ADD REPLY

Login before adding your answer.

Traffic: 579 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6