I posted this question in stackoverflow: http://stackoverflow.com/questions/40370538/parameters-and-auc-and-ic50-of-a-dose-response-curve regrading computation of AUC and IC50 from a log-logistic curve fitted to dose response data using PharmacoGx, I thought it would be helpful to share this with Bioconductor. I'll remove it if this is wrong to do.