Dear colleague, I have a question regarding the Affymetrix CDF Packages for BioConductor. We have installed BioConductor using the getBioC.R script on a Linux server and it seems to work fine. Regarding the Affymetrix CDF Packages we are a little bit lost where to place these files/directories after unpacking (gunzip & tar). After the command "R> eset <- rma(Data)" the software looks for a *cdf.rda file in /usr/lib/R/library/affy/data. When I take a *cdf.rda file from an unpacked Affymetrix CDF Package and place it in this requested directory then the software seems to generate data without error messages. However, since this is only one file of the CDF package, where are the remaining files and directories of an CDF package supposed to go? Thanks for your help, Thomas Thomas Girke Center for Plant Cell Biology (CEPCEB) Department of Botany and Plant Sciences University of California Riverside, CA 92521 E-mail: thomas.girke@ucr.edu Ph: 909-787-2469 Fax: 909-787-4437