Hi, I wanna do p value adjustment to several groups of raw p values obtained by two-way or three-way layout ANOVA (tissue, time and treat) on some microarray data. I have used step up FDR (mt.rawp2adjp in multtest package) to do the p value adjustment. I also wanna try step down FDR implemented as the function mt.maxT. However, the input of mt.maxT is not a group of raw p values just like mt.raw2adjp, but a 2-dimensional raw data. Could anyone tell me how to apply mt.maxT to my case? Thanks, Wuming