Can I adjust weights by group in dreamlet(), like in voomByGroup(), with a random effect?
1
0
Entering edit mode
birb • 0
@c7fb2467
Last seen 4 days ago
United States

Is it possible to adjust the weights used in dreamlet by group to account for distinct shapes of group-wise mean-variance trends (as is done by limma::voomByGroup ), but with a random effect in the formula?

dreamlet • 379 views
ADD COMMENT
1
Entering edit mode
@gordon-smyth
Last seen 1 hour ago
WEHI, Melbourne, Australia

voomByGroup() itself can handle a random effect if you pass arguments block and correlation to it, same as for voom().

ADD COMMENT
1
Entering edit mode

I agree with Gordon. This is not currently supported by dream

ADD REPLY

Login before adding your answer.

Traffic: 353 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6