Hey so I am currently trying to do a deconvolution in R using the granule tool. The code seems fine to me but I always get the error message ''sigMatrix should not contain missing values''. So I assume there is a problem with my reference data but I can't figure out what it is. Has anybode encountered this issue before. If so I would be very happy for help

library(granulator)
library(readr)
library(dplyr)
library(tibble)

# Define file paths
filtered_tpm_matrix_path <- "C:/Users/User/Desktop/Heidelberg/filtered_tpm_matrix.csv"
log2fc_file_path <- "C:/Users/User/Desktop/Heidelberg/reshaped_gene_clusters_log2FC.csv"
deconvolution_output_path <- "C:/Users/User/Desktop/Heidelberg/deconvolution_results.csv"

# Read the filtered TPM matrix and log2FC file
filtered_tpm_matrix <- read.csv(filtered_tpm_matrix_path, row.names = 1)
log2fc_genes <- read.csv(log2fc_file_path)

# Convert the filtered TPM matrix to a matrix if it's not already
filtered_tpm_matrix <- as.matrix(filtered_tpm_matrix)

# Inspect the data
head(filtered_tpm_matrix)
head(log2fc_genes)

# Run deconvolution
decon <- deconvolute(m = filtered_tpm_matrix, sigMatrix = log2fc_genes)

# Save the results to a CSV file
write.csv(decon, deconvolution_output_path, row.names = TRUE)