How should I know which platforms are available for TCGA methylation?
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Entering edit mode
@xiaofeiwang198266-13657
Last seen 5 hours ago
United States

As the code block here , screenshot below.

It worked to get data from platform of Illumina Human Methylation 27 for TCGA-B6-A0IM. But, when I tried to change the platform argument to "Illumina Methylation Epic", it gave me an error as below. I assumed Epic may not be available. Firstly, I thought it may relate to the packages version. But, the error is still there after updating TCGAbiolinks to the lastest one.

So, my question is how should I know the platform availability for TCGA? Thanks!

 query_met.hg38 <- GDCquery(
     project = "TCGA-BRCA", 
     data.category = "DNA Methylation", 
     data.type = "Methylation Beta Value",
     platform = "Illumina Methylation Epic", 
     barcode = c("TCGA-B6-A0IM")
 )


# include your problematic code here with any corresponding output 

--------------------------------------
o GDCquery: Searching in GDC database
--------------------------------------
Genome of reference: hg38
--------------------------------------------
oo Accessing GDC. This might take a while...
--------------------------------------------
ooo Project: TCGA-BRCA
--------------------
oo Filtering results
--------------------
Error in GDCquery(project = "TCGA-BRCA", data.category = "DNA Methylation",  : 
  Please set a valid platform argument from the list below:
  => Illumina Human Methylation 27
  => Illumina Human Methylation 450


other attached packages:
 [1] GenomicRanges_1.56.2 GenomeInfoDb_1.40.1  IRanges_2.38.1       S4Vectors_0.42.1     sesameData_1.22.0    ExperimentHub_2.12.0
 [7] AnnotationHub_3.12.0 BiocFileCache_2.12.0 dbplyr_2.5.0         BiocGenerics_0.50.0  TCGAbiolinks_2.32.0 

loaded via a namespace (and not attached):
 [1] DBI_1.2.3                   httr2_1.0.5                 biomaRt_2.60.1              rlang_1.1.4                
 [5] magrittr_2.0.3              matrixStats_1.4.1           compiler_4.4.1              RSQLite_2.3.7              
 [9] reshape2_1.4.4              png_0.1-8                   vctrs_0.6.5                 rvest_1.0.4                
[13] stringr_1.5.1               pkgconfig_2.0.3             crayon_1.5.3                fastmap_1.2.0              
[17] XVector_0.44.0              utf8_1.2.4                  tzdb_0.4.0                  preprocessCore_1.66.0      
[21] UCSC.utils_1.0.0            purrr_1.0.2                 bit_4.5.0                   xfun_0.48                  
[25] zlibbioc_1.50.0             cachem_1.1.0                jsonlite_1.8.9              progress_1.2.3             
[29] blob_1.2.4                  DelayedArray_0.30.1         BiocParallel_1.38.0         parallel_4.4.1             
[33] prettyunits_1.2.0           R6_2.5.1                    stringi_1.8.4               RColorBrewer_1.1-3         
[37] sesame_1.22.2               Rcpp_1.0.13                 SummarizedExperiment_1.34.0 knitr_1.48                 
[41] wheatmap_0.2.0              downloader_0.4              R.utils_2.12.3              readr_2.1.5                
[45] Matrix_1.7-0                tidyselect_1.2.1            abind_1.4-8                 yaml_2.3.10                
[49] codetools_0.2-20            curl_5.2.3                  lattice_0.22-6              tibble_3.2.1               
[53] plyr_1.8.9                  Biobase_2.64.0              withr_3.0.1                 KEGGREST_1.44.1            
[57] xml2_1.3.6                  Biostrings_2.72.1           pillar_1.9.0                BiocManager_1.30.25        
[61] filelock_1.0.3              MatrixGenerics_1.16.0       generics_0.1.3              BiocVersion_3.19.1         
[65] hms_1.1.3                   ggplot2_3.5.1               munsell_0.5.1               scales_1.3.0               
[69] glue_1.8.0                  tools_4.4.1                 data.table_1.16.2           XML_3.99-0.17              
[73] grid_4.4.1                  tidyr_1.3.1                 AnnotationDbi_1.66.0        colorspace_2.1-1           
[77] GenomeInfoDbData_1.2.12     cli_3.6.3                   rappdirs_0.3.3              fansi_1.0.6                
[81] S4Arrays_1.4.1              dplyr_1.1.4                 gtable_0.3.5                R.methodsS3_1.8.2          
[85] TCGAbiolinksGUI.data_1.24.0 digest_0.6.37               SparseArray_1.4.8           memoise_2.0.1              
[89] R.oo_1.26.0                 lifecycle_1.0.4             httr_1.4.7                  mime_0.12                  
[93] bit64_4.5.2

enter image description here

TCGAbiolinks • 181 views
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Entering edit mode
@james-w-macdonald-5106
Last seen 1 day ago
United States

Doesn't this tell you which platforms are available?

Error in GDCquery(project = "TCGA-BRCA", data.category = "DNA Methylation",  : 
  Please set a valid platform argument from the list below:
  => Illumina Human Methylation 27
  => Illumina Human Methylation 450
0
Entering edit mode

Yes, it does. But, I mean how should I know in advance or where can I find the information before running code. Because I have several projects which need downloading. I'd like to avoid the error in my loop. Sorry for the confusion.

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