User: CataVallejos

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CataVallejos10
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Location:
The Alan Turing Institute
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@CataVallejosM
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Last seen:
8 months, 1 week ago
Joined:
1 year, 2 months ago
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Posts by CataVallejos

<prev • 3 results • page 1 of 1 • next >
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Answer: A: Differential expressiong with two groups in BASiCS
... Indeed, I will expect that DESeq2 and BASiCS report similar results when assessing changes in mean expression between the groups. Said this, the main advantage of using BASiCS is the differential variability testing (through over-dispersion or, more recently, residual over-dispersion https://www.bio ...
written 8 months ago by CataVallejos10
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Answer: A: Differential expressiong with two groups in BASiCS
... Yes, you should run `BASiCS_MCMC` separately for each group of samples and then use those as the input of `BASiCS_TestDE`. Let me know if you have any issues while running the analysis.     ...
written 8 months ago by CataVallejos10
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Answer: A: BASiCS spike info for single cell RNA sequences or Bayesian statistics help
... Hello, Indeed, the current release of BASiCS (BioC 3.6) cannot be used without spike-ins. Recently, we extended the method to the no-spikes case and that is available in BioC devel (see also https://www.biorxiv.org/content/early/2017/12/21/237214).    However, I am afraid that BASiCS is *not* sui ...
written 8 months ago by CataVallejos10

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