User: emilio.marmol

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Posts by emilio.marmol

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Comment: C: DESeq2 for analyzing differential expression based on dispersion across samples
... I know, this is the reason why I took a somewhat alternative approach to calculate a dispersion matrix for each gene in each sample. The distribution of this new matrix fits a negative binomial distribution, at least this is what my data tells me. I used this new matrix to be embeded in clasical DES ...
written 9 months ago by emilio.marmol0
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Comment: C: DESeq2 for analyzing differential expression based on dispersion across samples
... I am not fully interested in assesing differences in global BCV distribution across groups, but in determining if differences in gene-wise BCV values across groups are different at a significant level. As you can see in ploted BCVs for each analyzed gene across groups, I am interested in differen ...
written 9 months ago by emilio.marmol0
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DESeq2 for analyzing differential expression based on dispersion across samples within groups, instead of based on expression means.
... Hello, I have a somewhat technical statistical question based on some analyses I have been dealing with while using DESeq2 software for determining differences in the expression of certain miRNAs between groups. We performed a small-RNAseq experiment based on 4 different groups with 12 animals eac ...
deseq2 dispersion written 9 months ago by emilio.marmol0 • updated 9 months ago by Michael Love25k

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