User: florian.hahne@novartis.com

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Before joining biomedical research in big pharma here at Novartis I have been a member of the Bioconductor core team in Seattle. My scientific interests are the analysis of genomics and genetics data in all colours and flavour, data visualisation and software engineering as well as integration and mining of various types of toxicology-related data.

I am the maintainer and co-author of a number of packages, including Gviz for visualization of data along genomic coordinates, cellHTS2 for the analysis of high-throughput cell-based assays, and some of the flow cytometry infrastructure packages.

Posts by florian.hahne@novartis.com

<prev • 224 results • page 1 of 23 • next >
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Comment: C: GVIZ - Manually assign transcript to stacks?
...   Did you try collapse=FALSE in the BiomartGeneRegionTrack constructor? Individual transcripts should never get collapsed, but just to make sure. There is no real control over the stacking as this tries to optimize for the available space, but you can do some tricks. For instance, including a tran ...
written 5 weeks ago by florian.hahne@novartis.com1.6k
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Comment: C: gviz ideogramTrack connection error
... In 99% of cases, this is an issue with the rtracklayer connection to UCSC. Gviz does not implement any of that functionality. I'd advise to test whether the rtracklayer UCSC functionality works for you, and if not, to reach out to the rtracklayer package maintainers. Florian ...
written 5 months ago by florian.hahne@novartis.com1.6k
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Answer: A: Gviz: Help figuring out `arguments imply differing number of rows: 0, 1` error
... Looks a lot like a bug to me.  data.frame(x1 = start(pairGaps) - 1, y1 = gy, x2 = end(pairGaps) + 1, y2 = gy, col = .dpOrDefault(GdObject, c("col.mates", "col"), .DEFAULT_BRIGHT_SHADED_COL), lwd = .dpOrDefault(GdObject, c("lwd.mates", "lwd"), 1), lty = .dpOrDefault(GdObject ...
written 7 months ago by florian.hahne@novartis.com1.6k
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Comment: C: Givz Doesn't plot coverage genetracks that are aligned against ensemble ref
... Obviously you will need to use the numerical chromosome name now also for plotting: plotTracks(list(idxTrack, axTrack, ensGenes ,mutant, wildtype),from=from, to=to, showTitle=T, showId=T, fontsize = 18, chromosome = 8) IGV is irrelevant, you are not changing your BAM file here. If you need more ...
written 8 months ago by florian.hahne@novartis.com1.6k
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Answer: A: Givz Doesn't plot coverage genetracks that are aligned against ensemble ref
... Are you sure that the chromosome names match? Sometimes you will only have the numeric part (e.g., 8) in your BAM file. A bit hard to say what is going wrong without seeing the actual data. Also, have you considered using the somewhat more specialised AlignmentsTrack class? It will be way more effi ...
written 8 months ago by florian.hahne@novartis.com1.6k
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Comment: C: R Gviz ideogram custom track
... I don't think that the initial band definitions make any sense. Why would you define bands that all start at the same location? Gviz doesn't really check the consistency of the band definition, but rather naively tries to draw polygons. I assume that is what you are seeing. Try defining non-overlapp ...
written 9 months ago by florian.hahne@novartis.com1.6k
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Answer: A: A bug when plotting Gviz data
... Hi Dadi, could you compile a short reproducible example for me to take a look at? Also pointing out what exactly gets messed up? Thanks, Florian ...
written 10 months ago by florian.hahne@novartis.com1.6k
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Answer: A: Gviz : sort reads in AlignmentsTracks and display reads containing indels
... You can't really sort reads in these visualisations. Gviz tries to arrange the reads in a way to minimize the vertical space that is needed for display. Also, indels are currently not supported. I am happy to add functionality to the package if somebody else in the developer realm want's to take a f ...
written 13 months ago by florian.hahne@novartis.com1.6k
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Comment: C: Regarding Gviz package
... I'd recommend for you to read up a bit on how to import Excel or tab delimited files into R, and also on the way Bioconductor handles genomic ranges. Gviz is very flexible in terms of inputs. You can provide a data.frame, a GRanges object, paths to various file formats or even populate the necessary ...
written 14 months ago by florian.hahne@novartis.com1.6k
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Answer: A: Gviz transcriptAnnotation with gff
... GeneRegionTrack objects are not simple wrappers around GRanges objects, but instead impose a certain structure like gene identifiers, transcript identifiers and human readable gene symbols. Thus it expects the input data to populate these required properties. Your repeat masker data is not really ge ...
written 14 months ago by florian.hahne@novartis.com1.6k

Latest awards to florian.hahne@novartis.com

Popular Question 13 months ago, created a question with more than 1,000 views. For Gviz question
Popular Question 13 months ago, created a question with more than 1,000 views. For displaying coverage RNAseq Gviz
Popular Question 13 months ago, created a question with more than 1,000 views. For Gviz problem to extract some track with UcscTrack like Broad ChromHMM
Popular Question 14 months ago, created a question with more than 1,000 views. For displaying coverage RNAseq Gviz
Scholar 15 months ago, created an answer that has been accepted. For A: Create custom IdeogramTrack (Gviz)
Teacher 16 months ago, created an answer with at least 3 up-votes. For A: Create custom IdeogramTrack (Gviz)
Scholar 16 months ago, created an answer that has been accepted. For A: Create custom IdeogramTrack (Gviz)
Scholar 17 months ago, created an answer that has been accepted. For A: Create custom IdeogramTrack (Gviz)
Scholar 17 months ago, created an answer that has been accepted. For A: Create custom IdeogramTrack (Gviz)
Teacher 17 months ago, created an answer with at least 3 up-votes. For A: Create custom IdeogramTrack (Gviz)
Teacher 2.2 years ago, created an answer with at least 3 up-votes. For A: Create custom IdeogramTrack (Gviz)
Scholar 2.2 years ago, created an answer that has been accepted. For A: Gviz: HighlightTrack on AlignmentsTrack - over pileup (reads) but behind coverag
Scholar 2.2 years ago, created an answer that has been accepted. For A: Gviz Color Filling
Scholar 2.2 years ago, created an answer that has been accepted. For A: Gviz: Set height to avoid empty whitespace below reads in an AlignmentsTrack?
Scholar 2.2 years ago, created an answer that has been accepted. For A: Gviz Color Filling
Scholar 2.2 years ago, created an answer that has been accepted. For A: Create custom IdeogramTrack (Gviz)
Scholar 2.2 years ago, created an answer that has been accepted. For A: Gviz: HighlightTrack on AlignmentsTrack - over pileup (reads) but behind coverag
Scholar 2.3 years ago, created an answer that has been accepted. For A: Gviz: How to color parts of transcript in BiomartGeneRegionTrack?
Scholar 2.3 years ago, created an answer that has been accepted. For A: Gviz: How to color parts of transcript in BiomartGeneRegionTrack?
Scholar 2.3 years ago, created an answer that has been accepted. For A: Gviz: Keep transcripts on same line even when using reverseStrand+showId?
Scholar 2.4 years ago, created an answer that has been accepted. For A: Gviz: How to color parts of transcript in BiomartGeneRegionTrack?
Scholar 2.4 years ago, created an answer that has been accepted. For A: Gviz: How to color parts of transcript in BiomartGeneRegionTrack?
Scholar 2.4 years ago, created an answer that has been accepted. For A: Gviz: HighlightTrack doesn't react to reverseStrand = TRUE ?
Scholar 2.4 years ago, created an answer that has been accepted. For A: Gviz: Keep transcripts on same line even when using reverseStrand+showId?
Teacher 3.1 years ago, created an answer with at least 3 up-votes. For A: Gviz - show plus and minus strand from a bam

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