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Posts by Guan
... Hi All, I understood from the preivous post "[BioC] ComBat_ Error in solve.default(t(design) %*% design): Lapack routine dgesv: system is exactly singular: U[4, 4] = 0" that this error is to do with the confounded batch and covariate status. I have the same ComBat_Error appeared when running surrog ...
ComBat_ Error in solve.default(t(design) %*% design): Lapack routine dgesv: system is exactly singular: U[4, 4] = 0
... Johnson, William Evan writes: > > ComBat should be done after normalization, and only of there are clear signs of batch effects after > normalization (either through significance testing, clustering, or principle component analysis). > > On Aug 21, 2013, at 12:33 AM, amit kumar subu ...
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